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I don't really like this, although this would give DP the same treatment as Fink. 

IMHO it would be better to search in the directories provided in LDFLAGS and/or 
OPT, that way users can choose if they want to use software from DP (or Fink).

Most of the required functionality seems to be there already. The only thing 
that's missing is enhancing variables like search_for_ssl_incs_in based on the 
include directories in OPT, but that's not necessary to pick up readline support.

E.g. '.../configure ... OPT=-I/opt/local/include LDFLAGS=-L/opt/local/include' 
should do the trick without patching python.