This is similar to bpo-44860, but in the other direction:

    $ docker run -it --rm -h=p fedora:34 bash
    ...
    [root@p /]# yum install python3 -y
    ...
    [root@p /]# type python3
    python3 is hashed (/usr/bin/python3)
    [root@p /]# python3 -V
    Python 3.9.6
    [root@p /]# python3.9 -q
    >>> from distutils.command.install import install
    >>> from distutils.dist import Distribution
    >>> c = install(Distribution())
    >>> c.home = '/foo'
    >>> c.finalize_options()
    >>> c.install_platlib
    '/foo/lib64/python'
    >>> import sysconfig
    >>> sysconfig.get_path('platlib', 'posix_home', vars={'home': '/root'})
    '/foo/lib/python'

sysconfig’s scheme should use `{platlib}` instead of hardcoding 'lib'.

Note that on Python 3.10+ the platlib values from distutils and sysconfig do match (since the distutils scheme is automatically generated from sysconfig), but the issue remains; sysconfig’s scheme should likely include `{platlib}` (adding Victor and Miro to confirm this).