Currently str.replace() has 3 arguments: old, new and count.
This issue suggests the new addition of another argument called case_insensitive (type bool, defaulted to False) which determines whether to ignore case when replacing said text or not.

Currently we have to use regex or logic (see https://stackoverflow.com/questions/919056/case-insensitive-replace), but it would just be a nice QoL feature to have a case_insensitive kwarg.