Thanks for submitting a very interesting issue! tkinter/Tk performance is not something we normally pay a lot of attention to. I did not attempt to run your application but I was able to see significant performance differences with your simple "help('modules') test. Before saying more, I want to test some additional configurations but I've run out of time for today. However, the differences don't seem to have anything to do with running on new M1 Macs as I was able to see them on a traditional Intel-based Mac running macOS 11.