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It seems that your patch is somewhat confused: It contains 
fragments of the SetPythonPath code, but fails to include 
the implementation of PyErr_Raise[Args].

I think the patch should also identify the places in the 
code that could make use of the offered simplifications 
(and change them to the new API), to get an impression of 
how general this API is. I'm +1 on the _Raise functions 
and -0 on the CallMethodArgs (why does it not support 
keyword arguments?).