> Do you mean all shebangs, including those with a native file path?

I like the idea as a whole, but ultimately end up disliking all the available options (in the context of py.exe, that is).

* Unix/virtual shebangs don't work reliably on Windows (as we can see :) )
* Native file path shebangs on Windows don't work on Unix

The scripts installed by pip &co. are their own executable wrappers, so the shebang shouldn't matter.

But, the python.org Windows installer associates .py files with py.exe, so it _does_ matter for double-click and PATHEXT scenarios.

Perhaps it is reasonable to redefine "/usr/bin/env python*" as "use %VIRTUALENV% python.exe if set" regardless of the specific version? I really don't want to add checks that require running Python - I'd rather bail out and recommend using "py" directly.