It turns out that both pickle and _pickle implement this feature, but the behavior is inconsistent.

- As a reminder, instances of slotted classes do not have a dict attribute (1)
- On the other side, when pickling slotted class instances, __getstate__ can return a tuple of 2 dicts. The first dict represents the __dict__ attribute. Because of (1), this first dict should simply be a sentinel value. In pickle, the condition is that it evaluates to False, but in _pickle, it should be explicitly None.

(- Finally, The second dict in state contains the slotted attribute. )

Here are the lines in the two files causing the inconsistent behavior:
https://github.com/python/cpython/blob/master/Modules/_pickle.c#L6236
https://github.com/python/cpython/blob/master/Lib/pickle.py#L1549

I included an example that illustrates it.