There should be a possibility to change the environment of a process created with multiprocessing.

For subprocess this is possible thanks to the "env" attribute.

Elaboration:
While it is trivial to change os.environ manually, in some cases this is not possible. 

For instance: creating a COM process on Windows; this process will always inherit the environment of the host process.
A workaround is to spawn a python process with a different environment which then will provide this to the child COM process.