The SSL EOF error is still common, but in the test, not in setUpClass(). Example:

http://buildbot.python.org/all/builders/AMD64%20FreeBSD%2010.x%20Shared%203.x/builds/874/steps/test/logs/stdio

======================================================================
ERROR: test_with_statement (test.test_nntplib.NetworkedNNTP_SSLTests)
----------------------------------------------------------------------
Traceback (most recent call last):
  File "/usr/home/buildbot/python/3.x.koobs-freebsd10/build/Lib/test/test_nntplib.py", line 241, in wrapped
    meth(self)
  File "/usr/home/buildbot/python/3.x.koobs-freebsd10/build/Lib/test/test_nntplib.py", line 263, in test_with_statement
    with self.NNTP_CLASS(self.NNTP_HOST, timeout=TIMEOUT, usenetrc=False) as server:
  File "/usr/home/buildbot/python/3.x.koobs-freebsd10/build/Lib/nntplib.py", line 1077, in __init__
    self.sock = _encrypt_on(self.sock, ssl_context, host)
  File "/usr/home/buildbot/python/3.x.koobs-freebsd10/build/Lib/nntplib.py", line 292, in _encrypt_on
    return context.wrap_socket(sock, server_hostname=hostname)
  File "/usr/home/buildbot/python/3.x.koobs-freebsd10/build/Lib/ssl.py", line 407, in wrap_socket
    _context=self, _session=session)
  File "/usr/home/buildbot/python/3.x.koobs-freebsd10/build/Lib/ssl.py", line 814, in __init__
    self.do_handshake()
  File "/usr/home/buildbot/python/3.x.koobs-freebsd10/build/Lib/ssl.py", line 1068, in do_handshake
    self._sslobj.do_handshake()
  File "/usr/home/buildbot/python/3.x.koobs-freebsd10/build/Lib/ssl.py", line 689, in do_handshake
    self._sslobj.do_handshake()
ssl.SSLEOFError: EOF occurred in violation of protocol (_ssl.c:864)

pythininfo:

ssl.HAS_SNI: True
ssl.OPENSSL_VERSION: OpenSSL 1.0.1u-freebsd  22 Sep 2016
ssl.OPENSSL_VERSION_INFO: (1, 0, 1, 21, 15)
ssl.OP_ALL: 0x800003ff
ssl.OP_NO_TLSv1_1: 0x10000000