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The bad news is that this is difficult to fix: the whole "frameworkinstall" 
sequence is a bit of a hack, and it works by overriding prefix to point 
into the bowels of the framework and then doing the equivalent of a 
"make install".

The good news is that if I understand correctly what you're trying to do, 
building to a staging area so you can package things for distribution 
later, there's another way to do this that does work: use the DESTROOT 
environment variable. If you do "DESTROOT=/tmp/py241 configure --
enable-frameworks" you'll get a tree ready for installation in /tmp/py241. 
But that assumes you can live with /tmp/py241/usr/local/bin.

If your needs are different reopen the bug and explain your use case and 
I'll think harder about a solution:-)