I successfully built Python on OS X 10.10 with the Intel compiler v15.  However, running the regression tests gives me a "segmentation fault: 11" on test_ascii_formated.  I think this has to do with libffi, because when I build with the --use-system-ffi flag (using a libffi that I built) all the regression tests pass, but I get a seg fault when I try to import ctypes.  Using python's libffi I can import ctypes, but I get seg faults in the tests.  Looking at libffi's homepage, it looks like x86-64 Mac OS X isn't on the list of officially supported platforms.  I tried contacting the libffi-discuss mailing list about this but have received no response in a month.  Please let me know what other information I can provide.