In Issue 19490, Piet van Oostrum suggested:
"I think future versions of Python should add the relevant information about how they are linked to Tcl/Tk in sysconfig. This would include the path of the include files, the shared libraries and the tcl files. Or a framework location on OS X if this is used. The setup.py for extensions that need to link to Tcl/Tk can then interrogate this information, and fall back to the current way, if it is not available."

Ned Deily replied:
"Piet, yes, I've been thinking of how to do that.  Unfortunately, it can only be a hint since, in the case of an "installer" Python, there is no guarantee that the header files on the build machine are available on the installed machine in the same location or even at all."