Noticed while debugging a problem with a test running on Windows 10 x86 that sizeof(wintypes.SIZE)==8 when I believe it should be 4. While using 

kernel32.CreateRemoteThread.argtypes = [wintypes.HANDLE, wintypes.LPCVOID, wintypes.DWORD, wintypes.LPCVOID, wintypes.LPCVOID, wintypes.DWORD, wintypes.LPDWORD] 

and  

kernel32.CreateRemoteThread(h_process, 0, 0, 0xbadadd, 0, 4, byref(thread_id))

It caused CreateRemoteThread to recieve 4 as the last argument, resulting in an access denied

The SIZE [1] type for a rectangle has nothing to do with SIZE_T [2], the integer type that's returned by C sizeof(). SIZE_T isn't defined in wintypes. A new issue can be opened to add more of the common data types to wintypes.

Here's an example for defining CreateRemoteThread:

    import ctypes
    from ctypes import wintypes

    kernel32 = ctypes.WinDLL('kernel32', use_last_error=True)

    SIZE_T = ctypes.c_size_t
    LPSECURITY_ATTRIBUTES = ctypes.c_void_p
    LPTHREAD_START_ROUTINE = ctypes.WINFUNCTYPE(wintypes.DWORD, wintypes.LPVOID)

    kernel32.CreateRemoteThread.restype = wintypes.HANDLE
    kernel32.CreateRemoteThread.argtypes = (
      wintypes.HANDLE,        # hProcess
      LPSECURITY_ATTRIBUTES,  # lpThreadAttributes
      SIZE_T,                 # dwStackSize
      LPTHREAD_START_ROUTINE, # lpStartAddress
      wintypes.LPVOID,        # lpParameter
      wintypes.DWORD,         # dwCreationFlags
      wintypes.LPDWORD)       # lpThreadId

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[1] https://docs.microsoft.com/en-us/windows/win32/api/windef/ns-windef-size
[2] https://docs.microsoft.com/en-us/windows/win32/winprog/windows-data-types#SIZE_T