Argument clinic uses some extra variables (like args, or noptargs, nargs etc.) for parsing. But there is a catch about these names, the generated code becomes wrong if there are any usages of them inside the signature. Encountered with this problem while working on *args support (in issue 20291). 

The possible solution is prefixing every argument in the parser with __clinic_ (__clinic_{var}) for preventing any kind of conflict. I'll draft a PR for this issue.

After preparing the patch and transforming all arguments with a __clinic_ prefix, I saw there are some actions that are taken by relying on the parser code. An example;
https://github.com/python/cpython/blob/8af4712a16e4b7d1b60f1faec13cd7a88da95f6a/Objects/codeobject.c#L616-L631

In that case, self was already replaced with __clinic_self so that code doesn't work. IMHO there should be an identifier to distinguish these cases like; <self>->co_argc etc. When we see such defaults we can just replace them with the prefixed version.