Thank you for these explanations.

I understand that we get a generic function to the cost of performances.

However, I think we should at least tell in the documentation that the constructor (ctypes.c_uint32 * len(t))(*t) is slow and that we can do much faster in some specific cases (e.g. an array of integers).

It would be even better to have some specific method(s) to do this in ctypes, instead of having to rely on an array.array just to build a ctypes array from a list. I am not familiar with CPython code, so I do not know if it would be easily feasible.