> pythoncom and comtypes use the value of sys.coinit_flags when imported

Good to know. Assume we'll add that as well.

Also, with respect to threading, we'd want to initialize on all new threads too. That will require a way to specify that a new thread should be STA/MTA. I'll think about this before proposing a solution (though since it's inherently an OS-specific specialization, having a separate function for this is a fairly safe way to do it).