test_distutils: Is the failure the same as before, or changed? Are you testing with new code that includes the Issue 27048 fix? It looks like test_distutils doesn’t support running directly via “unittest”. Perhaps try “python -m test -W test_distutils” or similar if you were previously only trying unittest.

Some of your new failures look like symptoms of running the test suite on out-of-date compiled modules. For test_ctypes, see Issue 27343; test_getargs2: Issue 26282; test_capi: Issue 26168.

strptime: Maybe the test suite is trying to report a string that contains both U+0092 and “é”, but cannot encode U+0092, and uses backslashreplace error handler.