Alexandre, this started after your latest checkin (to finish the framing work):

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FAIL: test_framing_large_objects (test.test_pickletools.OptimizedPickleTests) (proto=4)
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Traceback (most recent call last):
  File "C:\Code\Python\lib\test\pickletester.py", line 1354, in test_framing_large_objects
    self.assertGreaterEqual(n_frames, len(obj))
AssertionError: 1 not greater than or equal to 3

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FAIL: test_framing_many_objects (test.test_pickletools.OptimizedPickleTests) (proto=4)
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Traceback (most recent call last):
  File "C:\Code\Python\lib\test\pickletester.py", line 1342, in test_framing_many_objects
    self.FRAME_SIZE_TARGET * 1)
AssertionError: 368886.0 not less than or equal to 65536

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FAIL: test_optional_frames (test.test_pickletools.OptimizedPickleTests)
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Traceback (most recent call last):
  File "C:\Code\Python\lib\test\pickletester.py", line 1392, in test_optional_frames
    count_opcode(pickle.FRAME, pickled))
AssertionError: 1 not less than 1

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Ran 82 tests in 4.034s

FAILED (failures=3)
test test_pickletools failed
1 test failed:
    test_pickletools