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mktime() interprets its argument as local time; timegm() as 
UTC.  Generally speaking,

time.mktime(time.localtime())

returns int(time.time()), and so does

calendar.timegm(time.gmtime())

The OP appears to be right that the time module doesn't 
have an "inverse" for time.gmtime() in this sense.  Then 
again, the time functions inherited from C are generally a 
twisted thicket.