For example, the named-pipe filesystem (NPFS), doesn't return timestamps for pipes in the directory listing, so the timestamps are all 0 (i.e. 1601-01-01):

    >>> write_time = win32file.FindFilesW('//./pipe/*')[0][3]
    >>> format(write_time, '%Y-%m-%d %H:%M')
    '1601-01-01 00:00'

    >>> next(os.scandir('//./pipe')).stat().st_mtime
    -11644473600.0

I agree that a zero-valued NT timestamp should be converted to a zero-valued Unix timestamp. No one has a file that was created, modified, changed, or accessed in 1601.

As mentioned above, the 1601 date doesn't roundtrip in Windows as a Unix timestamp since dates before the Unix epoch aren't supported:

    >>> write_time.timestamp()
    -11644473600.0
    >>> datetime.fromtimestamp(write_time.timestamp())
    Traceback (most recent call last):
      File "<stdin>", line 1, in <module>
    OSError: [Errno 22] Invalid argument