For short-term / mid-term we have now decided to start python as seperate process and interact with some kind of IPC. That leads to a limited interaction model between python and the embedded app but it has the advantage that unloading is possible (by simply restarting python).

Hopefully, at some day python will have better support for unloading / reloading extension modules, but as some pointed out this will take time also until extension modules adopt new API discussed in the PEPs.

Thanks for discussion and information!