The clang folks have been hard at work making an ABI compatible backend to clang for Windows. Additionally they have created a cl compatible driver for clang, which can be used in lieu of cl itself. Clang-cl has been adopted to build Chrome on Windows http://blog.llvm.org/2018/03/clang-is-now-used-to-build-chrome-for.html, so I think it is stable enough to be considered for use.

Clang-cl has several advantages, such as computed goto support and many other optimizations which would make Python faster on Windows.

I would be happy to start contributing patches to further this goal, I already have a couple of small patches.