According to this nginx test https://www.nginx.com/blog/thread-pools-boost-performance-9x/ there is a huge boost in performance when using thread poll for File IO. It is postulated that when preadv2() & RWF_NONBLOCK feature are available it would further benefit (latency, thread sync, ...)

I am not a C coder so i can't just jump into this and code this feature (if i could i would have done it long ago). As Antoine mentioned, it needs to written at C (+ctypes) level.

I am willing to help, hit me up on #python user: stealth_