I'm also concerned that the slowness of namedtuple creation is causing people to avoid using it. I can see why we wouldn't want a complicated solution like using Argument Clinic, but it's not clear to me why Serhiy's approach in namedtuple-no-compile.patch was rejected. This approach could provide a speedup for all namedtuple instantiations without complicating the implementation. I wrote a similar implementation in https://github.com/JelleZijlstra/cpython/commit/5634af4ccfd06a2fabc2cc2cfcc9c014caf6f389 and found that it speeds up namedtuple creation, uses less code, and creates only one necessary backwards compatibility break (we no longer have _source).