I agree, the `--enable-shared` fix is nice, but I would also love to squash this bug.

An interesting piece of information: When I provide the full path to the executable (not just relying on the hashed python location), I see:

$ /Users/Adam/spack/opt/spack/darwin-sierra-x86_64/clang-8.0.0-apple/python-2.7.13-tjqn5npfo573q2jw3dumzhzctfd2vvdv/bin/python
Python 2.7.10 (default, Jul 30 2016, 19:40:32) 
[GCC 4.2.1 Compatible Apple LLVM 8.0.0 (clang-800.0.34)] on darwin
Type "help", "copyright", "credits" or "license" for more information.
>>> import sys
>>> print sys.version
2.7.10 (default, Jul 30 2016, 19:40:32) 
[GCC 4.2.1 Compatible Apple LLVM 8.0.0 (clang-800.0.34)]
>>> print sys.path
['', '/Users/Adam/spack/opt/spack/darwin-sierra-x86_64/clang-8.0.0-apple/python-2.7.13-tjqn5npfo573q2jw3dumzhzctfd2vvdv/lib/python27.zip', '/Users/Adam/spack/opt/spack/darwin-sierra-x86_64/clang-8.0.0-apple/python-2.7.13-tjqn5npfo573q2jw3dumzhzctfd2vvdv/lib/python2.7', '/Users/Adam/spack/opt/spack/darwin-sierra-x86_64/clang-8.0.0-apple/python-2.7.13-tjqn5npfo573q2jw3dumzhzctfd2vvdv/lib/python2.7/plat-darwin', '/Users/Adam/spack/opt/spack/darwin-sierra-x86_64/clang-8.0.0-apple/python-2.7.13-tjqn5npfo573q2jw3dumzhzctfd2vvdv/lib/python2.7/plat-mac', '/Users/Adam/spack/opt/spack/darwin-sierra-x86_64/clang-8.0.0-apple/python-2.7.13-tjqn5npfo573q2jw3dumzhzctfd2vvdv/lib/python2.7/plat-mac/lib-scriptpackages', '/Users/Adam/spack/opt/spack/darwin-sierra-x86_64/clang-8.0.0-apple/python-2.7.13-tjqn5npfo573q2jw3dumzhzctfd2vvdv/lib/python2.7/lib-tk', '/Users/Adam/spack/opt/spack/darwin-sierra-x86_64/clang-8.0.0-apple/python-2.7.13-tjqn5npfo573q2jw3dumzhzctfd2vvdv/lib/python2.7/lib-old', '/Users/Adam/spack/opt/spack/darwin-sierra-x86_64/clang-8.0.0-apple/python-2.7.13-tjqn5npfo573q2jw3dumzhzctfd2vvdv/lib/python2.7/lib-dynload', '/Users/Adam/.local/lib/python2.7/site-packages', '/Users/Adam/spack/opt/spack/darwin-sierra-x86_64/clang-8.0.0-apple/python-2.7.13-tjqn5npfo573q2jw3dumzhzctfd2vvdv/lib/python2.7/site-packages']

Note that I am building Python 2.7.13, not 2.7.10. Homebrew installs Python in /usr/local and that version is 2.7.12. My Ananconda installation is in ~/anaconda2 and is 2.7.13. However, the system Python installed at /usr is 2.7.10. Perhaps this is where it is picking up libraries from?

Here's some more debug information that could possibly be helpful. I have attached the output of:

$ /Users/Adam/spack/opt/spack/darwin-sierra-x86_64/clang-8.0.0-apple/python-2.7.13-tjqn5npfo573q2jw3dumzhzctfd2vvdv/bin/python -c 'from __future__ import print_function; import sysconfig; vars = sysconfig.get_config_vars(); [print(var, vars[var]) for var in vars]' > ~/python-config-vars.txt

Nothing in there looks particularly suspicious to me, but maybe you can find something fishy. I'll try out DYLD_PRINT_LIBRARIES next.