Sure, building _ssl fails with:
building '_ssl' extension
gcc -pthread -fPIC -fno-strict-aliasing -g -O2 -DNDEBUG -g -fwrapv -O3 -Wall -I. -IInclude -I./Include -I/usr/include -I/home/buildbot/build/sage/iras-1/iras_full/build
/sage-5.10.beta4/local/include -I/home/buildbot/local/iras/include -I/home/buildbot/build/sage/iras-1/iras_full/build/sage-5.10.beta4/spkg/build/python-2.7.5.p0/src/Inc
lude -I/home/buildbot/build/sage/iras-1/iras_full/build/sage-5.10.beta4/spkg/build/python-2.7.5.p0/src -c /home/buildbot/build/sage/iras-1/iras_full/build/sage-5.10.bet
a4/spkg/build/python-2.7.5.p0/src/Modules/_ssl.c -o build/temp.linux-ia64-2.7/home/buildbot/build/sage/iras-1/iras_full/build/sage-5.10.beta4/spkg/build/python-2.7.5.p0
/src/Modules/_ssl.o
gcc -pthread -shared -L/home/buildbot/build/sage/iras-1/iras_full/build/sage-5.10.beta4/local/lib -L/home/buildbot/build/sage/iras-1/iras_full/build/sage-5.10.beta4/loc
al/lib build/temp.linux-ia64-2.7/home/buildbot/build/sage/iras-1/iras_full/build/sage-5.10.beta4/spkg/build/python-2.7.5.p0/src/Modules/_ssl.o -L/usr/lib -L/lib -L/home
/buildbot/build/sage/iras-1/iras_full/build/sage-5.10.beta4/local/lib -L/home/buildbot/local/iras/lib -L. -lssl -lcrypto -lpython2.7 -o build/lib.linux-ia64-2.7/_ssl.so
/usr/bin/ld: /home/buildbot/local/iras/lib/libcrypto.a(obj_dat.o): @gprel relocation against dynamic symbol obj_cleanup_defer
/usr/bin/ld: /home/buildbot/local/iras/lib/libcrypto.a(obj_dat.o): @gprel relocation against dynamic symbol obj_cleanup_defer
/usr/bin/ld: final link failed: Nonrepresentable section on output
collect2: error: ld returned 1 exit status

But really: I think the main problem here is that _md5 isn't even attempted to build.