Quoting Victor Stinner from msg106669:

"""
It's maybe possible for write some 2to3 fixers for the following examples:

"...".encode("base64") => base64.b64encode("...")
"...".encode("rot13") => do nothing (but display a warning?)
"...".encode("zlib") => zlib.compress("...")
"...".encode("hex") => base64.b16encode("...")
"...".encode("bz2") => bz2.compress("...")

"...".decode("base64") => base64.b64decode("...")
"...".decode("rot13") => do nothing (but display a warning?)
"...".decode("zlib") => zlib.decompress("...")
"...".decode("hex") => base64.b16decode("...")
"...".decode("bz2") => bz2.decompress("...")
"""

Unfortunately I don't know where is the syntax for writing fixers.