diff --git a/Lib/test/test_getpath.py b/Lib/test/test_getpath.py
index eaf4a99279..d825389755 100644
--- a/Lib/test/test_getpath.py
+++ b/Lib/test/test_getpath.py
@@ -446,6 +446,73 @@ def test_custom_platlibdir_posix(self):
         actual = getpath(ns, expected)
         self.assertEqual(expected, actual)
 
+    def test_framework_macos(self):
+        """ Test framework layout on macOS """
+        ns = MockPosixNamespace(
+            os_name="darwin",
+            argv0="/Library/Frameworks/Python.framework/Versions/9.8/Resources/Python.app/Contents/MacOS/Python",
+            WITH_NEXT_FRAMEWORK=1,
+            PREFIX="/Library/Frameworks/Python.framework/Versions/9.8",
+            ENV___PYVENV_LAUNCHER__="/Library/Frameworks/Python.framework/Versions/9.8/bin/python9.8",
+            real_executable="/Library/Frameworks/Python.framework/Versions/9.8/Resources/Python.app/Contents/MacOS/Python",
+            library="/Library/Frameworks/Python.framework/Versions/9.8/Python",
+        )
+        ns.add_known_xfile("/Library/Frameworks/Python.framework/Versions/9.8/Resources/Python.app/Contents/MacOS/Python")
+        ns.add_known_xfile("/Library/Frameworks/Python.framework/Versions/9.8/bin/python9.8")
+        ns.add_known_xfile("/Library/Frameworks/Python.framework/Versions/9.8/lib/python9.8/lib-dynload")
+        expected = dict(
+            executable="/Library/Frameworks/Python.framework/Versions/9.8/bin/python9.8",
+            prefix="/Library/Frameworks/Python.framework/Versions/9.8",
+            exec_prefix="/Library/Frameworks/Python.framework/Versions/9.8",
+            base_executable="/Library/Frameworks/Python.framework/Versions/9.8/bin/python9.8",
+            base_prefix="/Library/Frameworks/Python.framework/Versions/9.8",
+            base_exec_prefix="/Library/Frameworks/Python.framework/Versions/9.8",
+            module_search_paths_set=1,
+            module_search_paths=[
+                "/Library/Frameworks/Python.framework/Versions/9.8/lib/python98.zip",
+                "/Library/Frameworks/Python.framework/Versions/9.8/lib/python9.8",
+                "/Library/Frameworks/Python.framework/Versions/9.8/lib/python9.8/lib-dynload",
+            ],
+        )
+        actual = getpath(ns, expected)
+        self.assertEqual(expected, actual)
+
+    def test_alt_framework_macos(self):
+        """ Test framework layout on macOS with alternate framework name
+
+        ``--with-framework-name=DebugPython``
+        """
+        ns = MockPosixNamespace(
+            os_name="darwin",
+            argv0="/Library/Frameworks/DebugPython.framework/Versions/9.8/Resources/Python.app/Contents/MacOS/DebugPython",
+            WITH_NEXT_FRAMEWORK=1,
+            PREFIX="/Library/Frameworks/DebugPython.framework/Versions/9.8",
+            ENV___PYVENV_LAUNCHER__="/Library/Frameworks/DebugPython.framework/Versions/9.8/bin/python9.8",
+            real_executable="/Library/Frameworks/DebugPython.framework/Versions/9.8/Resources/Python.app/Contents/MacOS/DebugPython",
+            library="/Library/Frameworks/DebugPython.framework/Versions/9.8/DebugPython",
+        )
+        ns.add_known_xfile("/Library/Frameworks/DebugPython.framework/Versions/9.8/Resources/Python.app/Contents/MacOS/DebugPython")
+        ns.add_known_xfile("/Library/Frameworks/DebugPython.framework/Versions/9.8/bin/python9.8")
+        ns.add_known_xfile("/Library/Frameworks/DebugPython.framework/Versions/9.8/lib/python9.8/lib-dynload")
+        expected = dict(
+            executable="/Library/Frameworks/DebugPython.framework/Versions/9.8/bin/python9.8",
+            prefix="/Library/Frameworks/DebugPython.framework/Versions/9.8",
+            exec_prefix="/Library/Frameworks/DebugPython.framework/Versions/9.8",
+            base_executable="/Library/Frameworks/DebugPython.framework/Versions/9.8/bin/python9.8",
+            base_prefix="/Library/Frameworks/DebugPython.framework/Versions/9.8",
+            base_exec_prefix="/Library/Frameworks/DebugPython.framework/Versions/9.8",
+            module_search_paths_set=1,
+            module_search_paths=[
+                "/Library/Frameworks/DebugPython.framework/Versions/9.8/lib/python98.zip",
+                "/Library/Frameworks/DebugPython.framework/Versions/9.8/lib/python9.8",
+                "/Library/Frameworks/DebugPython.framework/Versions/9.8/lib/python9.8/lib-dynload",
+            ],
+        )
+        actual = getpath(ns, expected)
+        self.assertEqual(expected, actual)
+
+
+
     def test_venv_macos(self):
         """Test a venv layout on macOS.
 
@@ -787,6 +854,7 @@ def __init__(self, *a, argv0=None, config=None, **kw):
         self["config"] = DEFAULT_CONFIG.copy()
         self["os_name"] = "posix"
         self["PLATLIBDIR"] = "lib"
+        self["WITH_NEXT_FRAMEWORK"] = 0
         super().__init__(*a, **kw)
         if argv0:
             self["config"]["orig_argv"] = [argv0]
diff --git a/Makefile.pre.in b/Makefile.pre.in
index 7b6f54a9ae..56a4c531f1 100644
--- a/Makefile.pre.in
+++ b/Makefile.pre.in
@@ -1218,6 +1218,7 @@ Modules/getpath.o: $(srcdir)/Modules/getpath.c Python/frozen_modules/getpath.h M
 		-DVERSION='"$(VERSION)"' \
 		-DVPATH='"$(VPATH)"' \
 		-DPLATLIBDIR='"$(PLATLIBDIR)"' \
+		-DPYTHONFRAMEWORK='"$(PYTHONFRAMEWORK)"' \
 		-o $@ $(srcdir)/Modules/getpath.c
 
 Programs/python.o: $(srcdir)/Programs/python.c
diff --git a/Modules/getpath.c b/Modules/getpath.c
index 5c646c9c83..b39bee9403 100644
--- a/Modules/getpath.c
+++ b/Modules/getpath.c
@@ -873,6 +873,7 @@ _PyConfig_InitPathConfig(PyConfig *config, int compute_path_config)
         !decode_to_dict(dict, "os_name", "nt") ||
 #elif defined(__APPLE__)
         !decode_to_dict(dict, "os_name", "darwin") ||
+        !int_to_dict(dict, "WITH_NEXT_FRAMEWORK", WITH_NEXT_FRAMEWORK) ||
 #else
         !decode_to_dict(dict, "os_name", "posix") ||
 #endif
diff --git a/Modules/getpath.py b/Modules/getpath.py
index f84e6e8afa..015d27e7b6 100644
--- a/Modules/getpath.py
+++ b/Modules/getpath.py
@@ -33,6 +33,7 @@
 # PREFIX            -- [in] sysconfig.get_config_var(...)
 # EXEC_PREFIX       -- [in] sysconfig.get_config_var(...)
 # PYTHONPATH        -- [in] sysconfig.get_config_var(...)
+# WITH_NEXT_FRAMEWORK   -- [in] sysconfig.get_config_var(...) (on macOS)
 # VPATH             -- [in] sysconfig.get_config_var(...)
 # PLATLIBDIR        -- [in] sysconfig.get_config_var(...)
 # PYDEBUGEXT        -- [in, opt] '_d' on Windows for debug builds
@@ -307,6 +308,14 @@ def search_up(prefix, *landmarks, test=isfile):
     executable = ENV_PYTHONEXECUTABLE or ENV___PYVENV_LAUNCHER__
     executable_dir = dirname(executable)
 
+    if os_name == 'darwin' and WITH_NEXT_FRAMEWORK:
+        #print(library)
+        # In a framework build the binary in {sys.exec_prefix}/bin is
+        # a stub executable that execs the real interpreter in an
+        # embedded app bundle. That bundle is an implementation detail
+        # and should not affect base_execuble.
+        base_executable = f"{dirname(library)}/bin/python{VERSION_MAJOR}.{VERSION_MINOR}"
+
 
 # ******************************************************************************
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