diff --git a/Doc/library/typing.rst b/Doc/library/typing.rst
--- a/Doc/library/typing.rst
+++ b/Doc/library/typing.rst
@@ -563,6 +563,10 @@
    As a shorthand for this type, :class:`bytes` can be used to
    annotate arguments of any of the types mentioned above.
 
+.. class:: Deque(deque, MutableSequence[T])
+
+   A generic version of :class:`collections.deque`.
+
 .. class:: List(list, MutableSequence[T])
 
    Generic version of :class:`list`.
diff --git a/Lib/test/test_typing.py b/Lib/test/test_typing.py
--- a/Lib/test/test_typing.py
+++ b/Lib/test/test_typing.py
@@ -1572,6 +1572,9 @@
     def test_list(self):
         self.assertIsSubclass(list, typing.List)
 
+    def test_deque(self):
+        self.assertIsSubclass(collections.deque, typing.Deque)
+
     def test_set(self):
         self.assertIsSubclass(set, typing.Set)
         self.assertNotIsSubclass(frozenset, typing.Set)
@@ -1642,6 +1645,14 @@
         self.assertIsSubclass(MyDefDict, collections.defaultdict)
         self.assertNotIsSubclass(collections.defaultdict, MyDefDict)
 
+    def test_no_deque_instantiation(self):
+        with self.assertRaises(TypeError):
+            typing.Deque()
+        with self.assertRaises(TypeError):
+            typing.Deque[T]()
+        with self.assertRaises(TypeError):
+            typing.Deque[int]()
+
     def test_no_set_instantiation(self):
         with self.assertRaises(TypeError):
             typing.Set()
diff --git a/Lib/typing.py b/Lib/typing.py
--- a/Lib/typing.py
+++ b/Lib/typing.py
@@ -59,6 +59,7 @@
     'SupportsRound',
 
     # Concrete collection types.
+    'Deque',
     'Dict',
     'DefaultDict',
     'List',
@@ -1771,6 +1772,15 @@
                             "use list() instead")
         return _generic_new(list, cls, *args, **kwds)
 
+class Deque(collections.deque, MutableSequence[T], extra=collections.deque):
+
+    __slots__ = ()
+
+    def __new__(cls, *args, **kwds):
+        if _geqv(cls, Deque):
+            raise TypeError("Type Deque cannot be instantiated; "
+                            "use deque() instead")
+        return _generic_new(collections.deque, cls, *args, **kwds)
 
 class Set(set, MutableSet[T], extra=set):