--- a/Makefile.pre.in
+++ b/Makefile.pre.in
@@ -474,7 +475,9 @@ all:		@DEF_MAKE_ALL_RULE@
 build_all:	$(BUILDPYTHON) oldsharedmods sharedmods gdbhooks Programs/_testembed python-config
 
 # Compile a binary with profile guided optimization.
-profile-opt:
+profile-opt: profile-opt.stamp
+
+profile-opt.stamp:
 	@if [ $(LLVM_PROF_ERR) = yes ]; then \
 		echo "Error: Cannot perform PGO build because llvm-profdata was not found in PATH" ;\
 		echo "Please add it to PATH and run ./configure again" ;\
@@ -492,6 +495,11 @@ profile-opt:
 	$(MAKE) clean
 	$(MAKE) build_all_use_profile
 	$(MAKE) profile-removal
+	# This is an expensive target to build and it does not have proper
+	# dependancy information for "make" to figure out if it needs to
+	# get re-built.  Instead, create a stamp file to remember that is
+	# is complete.  Need to run "make clean" before this will be re-built.
+	touch $@
 
 build_all_generate_profile:
 	$(MAKE) @DEF_MAKE_RULE@ CFLAGS_NODIST="$(CFLAGS) $(PGO_PROF_GEN_FLAG) @LTOFLAGS@" LDFLAGS="$(LDFLAGS) $(PGO_PROF_GEN_FLAG) @LTOFLAGS@" LIBS="$(LIBS)"
@@ -506,6 +514,10 @@ build_all_merge_profile:
 build_all_use_profile:
 	$(MAKE) @DEF_MAKE_RULE@ CFLAGS_NODIST="$(CFLAGS) $(PGO_PROF_USE_FLAG) @LTOFLAGS@" LDFLAGS="$(LDFLAGS) @LTOFLAGS@"
 
+.PHONY: profile-opt build_all_generate_profile run_profile_task
+.PHONY: build_all_merge_profile build_all_use_profile
+
+
 # Compile and run with gcov
 .PHONY=coverage coverage-lcov coverage-report
 coverage:
@@ -1596,7 +1608,7 @@ clean: pycremoval
 	find build -name 'fficonfig.h' -exec rm -f {} ';' || true
 	find build -name '*.py' -exec rm -f {} ';' || true
 	find build -name '*.py[co]' -exec rm -f {} ';' || true
-	-rm -f pybuilddir.txt
+	-rm -f pybuilddir.txt profile-opt.stamp
 	-rm -f Lib/lib2to3/*Grammar*.pickle
 	-rm -f Programs/_testembed Programs/_freeze_importlib
 	-find build -type f -a ! -name '*.gc??' -exec rm -f {} ';'