diff -r 4b64a049f451 Lib/test/test_compileall.py
--- a/Lib/test/test_compileall.py	Fri Aug 19 12:00:13 2016 +0300
+++ b/Lib/test/test_compileall.py	Wed Sep 07 16:59:51 2016 +1000
@@ -115,7 +115,16 @@
             except ValueError:
                 pass
 
-        self.assertTrue(compileall.compile_path(quiet=2))
+        # issue27322: Prevent spurious failures due to permissions
+        # Attempt to compile only those directories which are part of the
+        # current binary's subtree. For example, if Python is being run from
+        # the build directory (eg 'make test'), ignore all system paths.
+        basedir = os.path.dirname(sys.executable)
+        if basedir.endswith('/bin'):
+            basedir = os.path.dirname(basedir)
+        sys.path = [p for p in sys.path if p.startswith(basedir)]
+
+        self.assertTrue(compileall.compile_path(quiet=2, force=True))
 
         with test.test_importlib.util.import_state(path=[self.directory]):
             self.add_bad_source_file()