diff -r 4d3066d4a5df Lib/pickle.py
--- a/Lib/pickle.py	Sat Dec 20 20:58:28 2014 +0200
+++ b/Lib/pickle.py	Sun Dec 21 10:44:08 2014 +0200
@@ -242,7 +242,7 @@ class _Unframer:
             if not data:
                 self.current_frame = None
                 return self.file_readline()
-            if data[-1] != b'\n':
+            if data[-1] != b'\n'[0]:
                 raise UnpicklingError(
                     "pickle exhausted before end of frame")
             return data
diff -r 4d3066d4a5df Lib/test/pickletester.py
--- a/Lib/test/pickletester.py	Sat Dec 20 20:58:28 2014 +0200
+++ b/Lib/test/pickletester.py	Sun Dec 21 10:44:08 2014 +0200
@@ -1584,6 +1584,14 @@ class AbstractPickleTests(unittest.TestC
                             count_opcode(pickle.FRAME, pickled))
             self.assertEqual(obj, self.loads(some_frames_pickle))
 
+    def test_frame_readline(self):
+        pickled = b'\x80\x04\x95\x05\x00\x00\x00\x00\x00\x00\x00I42\n.'
+        #    0: \x80 PROTO      4
+        #    2: \x95 FRAME      5
+        #   11: I    INT        42
+        #   15: .    STOP
+        self.assertEqual(self.loads(pickled), 42)
+
     def test_nested_names(self):
         global Nested
         class Nested: