diff --git a/Include/objimpl.h b/Include/objimpl.h
--- a/Include/objimpl.h
+++ b/Include/objimpl.h
@@ -166,6 +166,28 @@
 #define PyObject_INIT_VAR(op, typeobj, size) \
     ( Py_SIZE(op) = (size), PyObject_INIT((op), (typeobj)) )
 
+#ifdef __clang__
+/* Clang warns about unused expressions like the expansions of PyObject_INIT and
+ * PyObject_INIT_VAR. Replace them by static inline definitions.
+ */
+static __inline__ PyObject* _PyObject_INIT(PyObject* op, PyTypeObject* typeobj)
+{
+	return PyObject_INIT(op, typeobj);
+}
+
+static __inline__ PyVarObject* _PyObject_INIT_VAR(PyVarObject* op, PyTypeObject* typeobj, Py_ssize_t n)
+{
+	return PyObject_INIT_VAR(op, typeobj, n);
+}
+
+
+#undef PyObject_INIT
+#undef PyObject_INIT_VAR
+
+#define PyObject_INIT(op, typeobj) _PyObject_INIT((PyObject*)op, typeobj)
+#define PyObject_INIT_VAR(op, typeobj, n) _PyObject_INIT_VAR((PyVarObject*)op, typeobj, n)
+#endif
+
 #define _PyObject_SIZE(typeobj) ( (typeobj)->tp_basicsize )
 
 /* _PyObject_VAR_SIZE returns the number of bytes (as size_t) allocated for a