diff --git a/Modules/_ctypes/cfield.c b/Modules/_ctypes/cfield.c
--- a/Modules/_ctypes/cfield.c
+++ b/Modules/_ctypes/cfield.c
@@ -52,7 +52,7 @@
 {
     CFieldObject *self;
     PyObject *proto;
-    Py_ssize_t size, align, length;
+    Py_ssize_t size, align;
     SETFUNC setfunc = NULL;
     GETFUNC getfunc = NULL;
     StgDictObject *dict;
@@ -106,7 +106,6 @@
     }
 
     size = dict->size;
-    length = dict->length;
     proto = desc;
 
     /*  Field descriptors for 'c_char * n' are be scpecial cased to
diff --git a/Modules/_io/bytesio.c b/Modules/_io/bytesio.c
--- a/Modules/_io/bytesio.c
+++ b/Modules/_io/bytesio.c
@@ -938,13 +938,11 @@
 bytesiobuf_getbuffer(bytesiobuf *obj, Py_buffer *view, int flags)
 {
     int ret;
-    void *ptr;
     bytesio *b = (bytesio *) obj->source;
     if (view == NULL) {
         b->exports++;
         return 0;
     }
-    ptr = (void *) obj;
     ret = PyBuffer_FillInfo(view, (PyObject*)obj, b->buf, b->string_size,
                             0, flags);
     if (ret >= 0) {
diff --git a/Modules/_sqlite/connection.c b/Modules/_sqlite/connection.c
--- a/Modules/_sqlite/connection.c
+++ b/Modules/_sqlite/connection.c
@@ -673,7 +673,6 @@
 {
     PyObject* function_result = NULL;
     PyObject** aggregate_instance;
-    PyObject* aggregate_class;
 
 #ifdef WITH_THREAD
     PyGILState_STATE threadstate;
@@ -681,8 +680,6 @@
     threadstate = PyGILState_Ensure();
 #endif
 
-    aggregate_class = (PyObject*)sqlite3_user_data(context);
-
     aggregate_instance = (PyObject**)sqlite3_aggregate_context(context, sizeof(PyObject*));
     if (!*aggregate_instance) {
         /* this branch is executed if there was an exception in the aggregate's
diff --git a/Modules/_sqlite/cursor.c b/Modules/_sqlite/cursor.c
--- a/Modules/_sqlite/cursor.c
+++ b/Modules/_sqlite/cursor.c
@@ -126,11 +126,9 @@
 
 static void pysqlite_cursor_dealloc(pysqlite_Cursor* self)
 {
-    int rc;
-
     /* Reset the statement if the user has not closed the cursor */
     if (self->statement) {
-        rc = pysqlite_statement_reset(self->statement);
+        pysqlite_statement_reset(self->statement);
         Py_DECREF(self->statement);
     }
 
@@ -529,7 +527,7 @@
 
     if (self->statement != NULL) {
         /* There is an active statement */
-        rc = pysqlite_statement_reset(self->statement);
+        pysqlite_statement_reset(self->statement);
     }
 
     operation_cstr = _PyUnicode_AsStringAndSize(operation, &operation_len);
@@ -734,7 +732,7 @@
         }
 
         if (multiple) {
-            rc = pysqlite_statement_reset(self->statement);
+            pysqlite_statement_reset(self->statement);
         }
         Py_XDECREF(parameters);
     }
diff --git a/Modules/_sqlite/statement.c b/Modules/_sqlite/statement.c
--- a/Modules/_sqlite/statement.c
+++ b/Modules/_sqlite/statement.c
@@ -369,11 +369,9 @@
 
 void pysqlite_statement_dealloc(pysqlite_Statement* self)
 {
-    int rc;
-
     if (self->st) {
         Py_BEGIN_ALLOW_THREADS
-        rc = sqlite3_finalize(self->st);
+        sqlite3_finalize(self->st);
         Py_END_ALLOW_THREADS
     }
 
diff --git a/Modules/_ssl.c b/Modules/_ssl.c
--- a/Modules/_ssl.c
+++ b/Modules/_ssl.c
@@ -354,7 +354,6 @@
 
     /* Actually negotiate SSL connection */
     /* XXX If SSL_do_handshake() returns 0, it's also a failure. */
-    sockstate = 0;
     do {
         PySSL_BEGIN_ALLOW_THREADS
         ret = SSL_do_handshake(self->ssl);
@@ -1090,7 +1089,6 @@
         goto error;
     }
     do {
-        err = 0;
         PySSL_BEGIN_ALLOW_THREADS
         len = SSL_write(self->ssl, buf.buf, buf.len);
         err = SSL_get_error(self->ssl, len);
@@ -1226,7 +1224,6 @@
         }
     }
     do {
-        err = 0;
         PySSL_BEGIN_ALLOW_THREADS
         count = SSL_read(self->ssl, mem, len);
         err = SSL_get_error(self->ssl, count);
diff --git a/Modules/_tkinter.c b/Modules/_tkinter.c
--- a/Modules/_tkinter.c
+++ b/Modules/_tkinter.c
@@ -2005,7 +2005,7 @@
 PythonCmd(ClientData clientData, Tcl_Interp *interp, int argc, char *argv[])
 {
     PythonCmd_ClientData *data = (PythonCmd_ClientData *)clientData;
-    PyObject *self, *func, *arg, *res;
+    PyObject *func, *arg, *res;
     int i, rv;
     Tcl_Obj *obj_res;
 
@@ -2014,7 +2014,6 @@
     /* TBD: no error checking here since we know, via the
      * Tkapp_CreateCommand() that the client data is a two-tuple
      */
-    self = data->self;
     func = data->func;
 
     /* Create argument list (argv1, ..., argvN) */
diff --git a/Modules/arraymodule.c b/Modules/arraymodule.c
--- a/Modules/arraymodule.c
+++ b/Modules/arraymodule.c
@@ -876,7 +876,6 @@
     if (Py_SIZE(self) > 0) {
         if (n < 0)
             n = 0;
-        items = self->ob_item;
         if ((self->ob_descr->itemsize != 0) &&
             (Py_SIZE(self) > PY_SSIZE_T_MAX / self->ob_descr->itemsize)) {
             return PyErr_NoMemory();
diff --git a/Modules/audioop.c b/Modules/audioop.c
--- a/Modules/audioop.c
+++ b/Modules/audioop.c
@@ -513,7 +513,6 @@
 
     best_result = result;
     best_j = 0;
-    j = 0;
 
     for ( j=1; j<=len1-len2; j++) {
         aj_m1 = (double)cp1[j-1];
@@ -599,7 +598,6 @@
 
     best_result = result;
     best_j = 0;
-    j = 0;
 
     for ( j=1; j<=len1-len2; j++) {
         aj_m1 = (double)cp1[j-1];
@@ -1433,7 +1431,6 @@
     if ( state == Py_None ) {
         /* First time, it seems. Set defaults */
         valpred = 0;
-        step = 7;
         index = 0;
     } else if ( !PyArg_ParseTuple(state, "ii", &valpred, &index) )
         return 0;
@@ -1534,7 +1531,6 @@
     if ( state == Py_None ) {
         /* First time, it seems. Set defaults */
         valpred = 0;
-        step = 7;
         index = 0;
     } else if ( !PyArg_ParseTuple(state, "ii", &valpred, &index) )
         return 0;
diff --git a/Modules/main.c b/Modules/main.c
--- a/Modules/main.c
+++ b/Modules/main.c
@@ -577,7 +577,6 @@
     if ((p = Py_GETENV("PYTHONEXECUTABLE")) && *p != '\0') {
         wchar_t* buffer;
         size_t len = strlen(p);
-        size_t r;
 
         buffer = malloc(len * sizeof(wchar_t));
         if (buffer == NULL) {
@@ -585,7 +584,7 @@
                "not enough memory to copy PYTHONEXECUTABLE");
         }
 
-        r = mbstowcs(buffer, p, len);
+        mbstowcs(buffer, p, len);
         Py_SetProgramName(buffer);
         /* buffer is now handed off - do not free */
     } else {
diff --git a/Objects/floatobject.c b/Objects/floatobject.c
--- a/Objects/floatobject.c
+++ b/Objects/floatobject.c
@@ -197,7 +197,6 @@
             Py_DECREF(s_buffer);
             return NULL;
         }
-        last = s + len;
     }
     else if (PyObject_AsCharBuffer(v, &s, &len)) {
         PyErr_SetString(PyExc_TypeError,
diff --git a/Objects/obmalloc.c b/Objects/obmalloc.c
--- a/Objects/obmalloc.c
+++ b/Objects/obmalloc.c
@@ -1775,7 +1775,6 @@
      * will be living in full pools -- would be a shame to miss them.
      */
     for (i = 0; i < maxarenas; ++i) {
-        uint poolsinarena;
         uint j;
         uptr base = arenas[i].address;
 
@@ -1784,7 +1783,6 @@
             continue;
         narenas += 1;
 
-        poolsinarena = arenas[i].ntotalpools;
         numfreepools += arenas[i].nfreepools;
 
         /* round up to pool alignment */
diff --git a/Objects/unicodeobject.c b/Objects/unicodeobject.c
--- a/Objects/unicodeobject.c
+++ b/Objects/unicodeobject.c
@@ -5412,7 +5412,6 @@
         if (!result)
             return NULL;
         for (i = 0; i < 256; i++) {
-            key = value = NULL;
             key = PyLong_FromLong(decode[i]);
             value = PyLong_FromLong(i);
             if (!key || !value)
@@ -6961,7 +6960,6 @@
             return NULL;
         i = 0;
         p = u->str;
-        e = self->length - str1->length;
         if (str1->length > 0) {
             while (n-- > 0) {
                 /* look for next match */
diff --git a/Parser/parsetok.c b/Parser/parsetok.c
--- a/Parser/parsetok.c
+++ b/Parser/parsetok.c
@@ -127,7 +127,7 @@
 {
     parser_state *ps;
     node *n;
-    int started = 0, handling_import = 0, handling_with = 0;
+    int started = 0, handling_import = 0;
 
     if ((ps = PyParser_New(g, start)) == NULL) {
         fprintf(stderr, "no mem for new parser\n");
@@ -154,7 +154,7 @@
         }
         if (type == ENDMARKER && started) {
             type = NEWLINE; /* Add an extra newline */
-            handling_with = handling_import = 0;
+            handling_import = 0;
             started = 0;
             /* Add the right number of dedent tokens,
                except if a certain flag is given --
diff --git a/Python/ast.c b/Python/ast.c
--- a/Python/ast.c
+++ b/Python/ast.c
@@ -3231,7 +3231,6 @@
     const char *end;
 
     if (encoding == NULL) {
-        buf = (char *)s;
         u = NULL;
     } else {
         /* check for integer overflow */
diff --git a/Python/bltinmodule.c b/Python/bltinmodule.c
--- a/Python/bltinmodule.c
+++ b/Python/bltinmodule.c
@@ -37,7 +37,7 @@
 {
     PyObject *func, *name, *bases, *mkw, *meta, *prep, *ns, *cell;
     PyObject *cls = NULL;
-    Py_ssize_t nargs, nbases;
+    Py_ssize_t nargs;
 
     assert(args != NULL);
     if (!PyTuple_Check(args)) {
@@ -61,7 +61,6 @@
     bases = PyTuple_GetSlice(args, 2, nargs);
     if (bases == NULL)
         return NULL;
-    nbases = nargs - 2;
 
     if (kwds == NULL) {
         meta = NULL;
@@ -766,7 +765,6 @@
 {
     PyObject *v;
     PyObject *prog, *globals = Py_None, *locals = Py_None;
-    int plain = 0;
 
     if (!PyArg_UnpackTuple(args, "exec", 1, 3, &prog, &globals, &locals))
         return NULL;
@@ -775,7 +773,6 @@
         globals = PyEval_GetGlobals();
         if (locals == Py_None) {
             locals = PyEval_GetLocals();
-            plain = 1;
         }
         if (!globals || !locals) {
             PyErr_SetString(PyExc_SystemError,