diff -r d2c464d2ee82 Lib/site.py
--- a/Lib/site.py	Sat Jul 03 15:57:30 2010 +0200
+++ b/Lib/site.py	Thu Jul 29 16:57:50 2010 -0400
@@ -102,7 +102,10 @@
         # Filter out duplicate paths (on case-insensitive file systems also
         # if they only differ in case); turn relative paths into absolute
         # paths.
-        dir, dircase = makepath(dir)
+        try:
+            dir, dircase = makepath(dir)
+        except os.error:
+            continue
         if not dircase in known_paths:
             L.append(dir)
             known_paths.add(dircase)
diff -r d2c464d2ee82 Lib/sysconfig.py
--- a/Lib/sysconfig.py	Sat Jul 03 15:57:30 2010 +0200
+++ b/Lib/sysconfig.py	Thu Jul 29 16:57:50 2010 -0400
@@ -434,8 +434,12 @@
         # from a different directory.
         if _PYTHON_BUILD and os.name == "posix":
             base = _PROJECT_BASE
+            try:
+                cwd = os.getcwd()
+            except os.error:
+                cwd = None
             if (not os.path.isabs(_CONFIG_VARS['srcdir']) and
-                base != os.getcwd()):
+                base != cwd):
                 # srcdir is relative and we are not in the same directory
                 # as the executable. Assume executable is in the build
                 # directory and make srcdir absolute.