Index: Objects/fileobject.c
===================================================================
--- Objects/fileobject.c	(revision 73576)
+++ Objects/fileobject.c	(working copy)
@@ -1889,6 +1889,14 @@
 	Py_RETURN_NONE;
 }
 
+static PyObject *
+file_reduce(PyObject *f)
+{
+	PyErr_Format(PyExc_TypeError, "cannot pickle %.200s objects",
+		     Py_TYPE(f)->tp_name);
+	return NULL;
+}
+
 PyDoc_STRVAR(readline_doc,
 "readline([size]) -> next line from the file, as a string.\n"
 "\n"
@@ -1998,6 +2006,7 @@
 	{"isatty",    (PyCFunction)file_isatty,   METH_NOARGS,  isatty_doc},
 	{"__enter__", (PyCFunction)file_self,     METH_NOARGS,  enter_doc},
 	{"__exit__",  (PyCFunction)file_exit,     METH_VARARGS, exit_doc},
+	{"__reduce__", (PyCFunction)file_reduce,  METH_NOARGS, NULL},
 	{NULL,	      NULL}		/* sentinel */
 };
 
Index: Lib/test/test_file2k.py
===================================================================
--- Lib/test/test_file2k.py	(revision 73576)
+++ Lib/test/test_file2k.py	(working copy)
@@ -2,6 +2,7 @@
 import os
 import unittest
 import itertools
+import pickle
 import time
 import threading
 from array import array
@@ -123,6 +124,11 @@
     def testReadWhenWriting(self):
         self.assertRaises(IOError, self.f.read)
 
+    def testPicklingIsDisabled(self):
+        for protocol in range(pickle.HIGHEST_PROTOCOL + 1):
+            self.assertRaises(TypeError, pickle.dumps, self.f, protocol)
+
+
 class OtherFileTests(unittest.TestCase):
 
     def testOpenDir(self):