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Ah, that's a bug in meld. It shouldn't do
gettext.bindtextdomain, but locale.bindtextdomain (although
gtk.glade.bindtextdomain has the same effect).

It is intentional that the Python gettext implementation and
the C library's gettext implementation are separate. If you
want to use the C library's gettext, you should use the
locale.* functions; if you want the pure-Python
implementation, use gettext.*.

Closing as a third-party bug.