I ran perf.py on long_fl.patch of issue #26341. It looks slower and has no impact on such macro benchmark.

~/bin/taskset_isolated.py time python3 -u perf.py --rigorous ../default/python.orig ../default/python_long_fl

# python rev 37bacf3fa1f5

Report on Linux smithers 4.3.4-300.fc23.x86_64 #1 SMP Mon Jan 25 13:39:23 UTC 2016 x86_64 x86_64
Total CPU cores: 8

### chameleon_v2 ###
Min: 5.660445 -> 5.809548: 1.03x slower
Avg: 5.707313 -> 5.851431: 1.03x slower
Significant (t=-31.76)
Stddev: 0.03655 -> 0.02690: 1.3585x smaller

### json_dump_v2 ###
Min: 2.745682 -> 2.819627: 1.03x slower
Avg: 2.769530 -> 2.838116: 1.02x slower
Significant (t=-42.78)
Stddev: 0.01019 -> 0.01238: 1.2147x larger

### regex_v8 ###
Min: 0.041680 -> 0.041081: 1.01x faster
Avg: 0.042383 -> 0.041265: 1.03x faster
Significant (t=6.49)
Stddev: 0.00122 -> 0.00121: 1.0077x smaller

The following not significant results are hidden, use -v to show them:
2to3, django_v3, fastpickle, fastunpickle, json_load, nbody, tornado_http.