Thanks for the patch to configure.ac. It appears to work on OS X 10.4 and it should on any other system with an older version of sqlite3 installed. However, I think a better approach is to just change the two problematic references in Modules/_sqlite/connection.c to the older backwards compatible form.  The current sqlite3.h file explicitly supports the older type for backward compatibility for exactly this kind of case.  If so, why add unnecessary magic to Python's configure?  Presumably the sqlite3 project will need to continue to support both definitions indefinitely.  Perhaps Petri can chime in here as he made the change to include the new types.  Attached is a new patch tested on OS X 10.4 and 10.7.