array.array has all of the methods required by collections.MutableSequence, but:

>>> import array
>>> import collections
>>> isinstance(array.array, collections.MutableSequence)
False

Thanks for the bug report, Alexander. This is related, if not a superseder, of: https://bugs.python.org/issue29727

Thanks for taking a look at this. I think array is little used, so registering it as a member of some of the abstract base classes in collections could easily have been overlooked.

One of the prerequisites for membership in MutableSequence is a .clear() method, and array doesn't have one, though there is no reason why it shouldn't. Here's the workaround that I'm using:

import array
import collections

class array(array.array,
            collections.MutableSequence):
    __slots__ = ()
    
    def __reversed__(self):
        # this is a bit hacky
        return reversed(self.tolist())
        
    def clear(self):
        self.__setitem__(slice(None), self.__class__(self.typecode))
        
Here are some results:

>>> a = array('f', [1,2,3,4])
>>> list(reversed(a))
[4.0, 3.0, 2.0, 1.0]
>>> a.clear()
>>> a
array('f')

As Jim mentioned, issue 29727 also discusses registering array.array.

See issue 23864, issue 25737, issue 35190, and issue 35349 for discussions about collections.abc in general.

Closing this as a duplicate.