Applies to 2.7.10 and 2.7.12:

Installed LinuxCNC from source at https://github.com/LinuxCNC/linuxcnc :
./configure --with-realtime=uspace --enable-simulator --enable-non-distributable=yes --prefix=/usr --libdir=/usr/lib64
make
make install

Configured device as per attached files, that's a simulated XYZ-mill.

Now start application with: 
linuxcnc linuxcnc/configs/my-mill/my-mill.ini

The "Manual Control Widget" has a radio button denoted "X", "Y", "Z" with values "x", "y" and "z" to select the active axis. "X" and "Z" work as desired, but "Y" does not. Instead:

Exception in Tkinter callback
Traceback (most recent call last):
  File "/usr/lib64/python2.7/lib-tk/Tkinter.py", line 1537, in __call__
    return self.func(*args)
  File "/usr/bin/axis", line 2323, in jog_plus
    a = "xyzabcuvw".index(a)
ValueError: substring not found

Reason: The Tcl button variable "current_axis" gets "y" assigned to as desired. The corresponding python variable "a" however, gets "True". I've tracked that down to "FromObj" in "_tkinter.c" where "value->typePtr" equals "app->OldBooleanType". 

In 2.7.8 and 2.7.9 the behavior is ok, but in 2.7.10 and 2.7.12 button value "y" (and of course "yes", "no" etc.) is transformed into boolean a value ...    

This change of behaviour depends only on _tkinter.so, exchanging just *this single* file makes the problem (dis-) appear.

Any chance you could provide a simple reproducer?  We'll need something for a unit test.

I'm afraid I don't know Tcl nor python good enough to be able to strip this down to a reasonably simple test case.

However, I wonder what's going on there:

When the Tcl variable holding the radiobutton's value contains "x", "z", ..., value->typePtr always equals NULL in "FromObj" (both 2.7.8 and 2.7.12). But if the variable contains "y", "yes" etc., value->typePtr always equals app->OldBooleanType (again 2.7.8 and 2.7.12). And tcl8.6 has only one boolean type according to tclInt.h???

Now 2.7.8 doesn't handle that OldBooleanType in FromObj in any special way, whereas 2.7.12 does.

BTW: Setting Tkinter.wantobjects = 0 cures the problem but that's certainly not a sensible approach.

This problem was reported for 2.7 without a manageable reproducer. I suggest we close it because it's unlikely that anyone will want to investigate this now unless it's reported again for a supported python version.