I installed Python 2.7.5 including tests using the MSI installer from http://www.python.org/ftp/python/2.7.5/python-2.7.5.amd64.msi Running 

python.exe -m test.regrtest -v test_list

consumes all available memory and renders the my system completely unusable. I had to reboot. The problem is caused by the test case "test_overflow". If you run the test with an imposed memory limit, e.g. by using ulimitnt (http://code.google.com/p/ulimitnt/) , test_overflow passes.

I propose to skip this test on Win64.

I take it you have more than 16GB of RAM?
What happens if you replace "sys.maxint" with "sys.maxsize" in test_overflow?

Note: "test_overflow" can be found in Python2.7/Lib/test/test_list.py

> I take it you have more than 16GB of RAM?
I used a system with 16GB Ram.

> What happens if you replace "sys.maxint" with "sys.maxsize" in test_overflow?
The test passes. Both mul and imul raise MemoryError.

What if anything needs to be done here?

Currently, if you run the test suite of a 64bit Windows python installation it consumes all your memory and - depending on your RAM and swap space - you system becomes unusable. That's a behaviour nobody expects.

I didn't look into the implementation of the test case test_list. Therefore I can't make a proposal what to change. Obviously there are at least two options: 
- skip the test
- replace "sys.maxint" with "sys.maxsize" in test_overflow

Definitely this test should be decorated as bigmemtest. Here are patches.

I was wrong. Here should be just sys.maxsize. With sys.maxint the test should consume about 32 GB of memory and then fail on assertion (imul requires even 40 GB, but the test fails earlier).

New changeset 217485e80a32 by Serhiy Storchaka in branch '2.7':
Issue #18004: test_overflow in test_list by mistake consumed 40 GiB of memory
http://hg.python.org/cpython/rev/217485e80a32