Reporting this as requested by Antoine Pitrou: Under certain circumstances in Python 3.2 (r32:88445) it's possible for buffered I/O to lose data before it is written and/or return the wrong results when reading. I tripped over this issue whilst writing an assembler which first writes out a bunch of binary data and then goes back over it in a somewhat arbitrary order patching addresses.

The following code demonstrates the issue:

[code]
START = 0
MID = 1
LENGTH = 4

def test(buffering):
    f = open("test.bin", "w+b", buffering = buffering)
    for i in range(LENGTH):
        f.write(b'\x00')
    f.seek(MID)
    f.read(1)
    f.write(b'\x00')
    f.seek(MID)
    f.write(b'\x01')
    f.seek(START)
    f.seek(MID)
    print(f.read(1))
    f.close()

print("Buffered result: ")
test(-1)
print("Unbuffered result:")
test(0)
[end code]

Output on both Gentoo and Vista is:
    Buffered result:
    b'\x00'
    Unbuffered result:
    b'\x01'

Expected output is b'\x01' in both cases.

The issue is reproducible with larger files provided that the constants are increased ~proportionally (START 0, MID 500, LENGTH 1000 for example). Transposing the buffered/unbuffered tests and/or using different buffer sizes for the buffered test seem have no effect. 

The lengthy code at this URL also demonstrates the issue: http://pastebin.com/xqrzKr5D The above was produced from this code, which was autogenerated by intercepting my assembler's output.

If you add "from _pyio import open" to the example, unbuffered and buffered tests give the same result :-)

Here is a patch with assorted tests.

open("test.bin", "w+b", buffering=-1) creates a 
BufferedRandom object. In the _pyio module, BufferedRandom overrides the write() method to "undo readahead", whereas the _io module reuses bufferedwriter_write() for bufferedrandom_methods and bufferedwriter_methods.

I suppose that the problem is "just" that _io.BufferedRandom.write() doesn't undo readahead.

New changeset 89f77afac947 by Antoine Pitrou in branch '3.1':
Issue #12062: Fix a flushing bug when doing a certain type of I/O sequence
http://hg.python.org/cpython/rev/89f77afac947

New changeset 47ca1244a929 by Antoine Pitrou in branch '3.2':
Issue #12062: Fix a flushing bug when doing a certain type of I/O sequence
http://hg.python.org/cpython/rev/47ca1244a929

New changeset 05e0227e3879 by Antoine Pitrou in branch 'default':
Issue #12062: Fix a flushing bug when doing a certain type of I/O sequence
http://hg.python.org/cpython/rev/05e0227e3879

New changeset 0d24d4c537a6 by Antoine Pitrou in branch '2.7':
Issue #12062: In the `io` module, fix a flushing bug when doing a certain
http://hg.python.org/cpython/rev/0d24d4c537a6

Should be fixed now. Again, thank you reporting this bug!