diff -r 19464d77ec2e Lib/test/test_wsgiref.py
--- a/Lib/test/test_wsgiref.py	Sun Dec 29 23:38:55 2013 +0000
+++ b/Lib/test/test_wsgiref.py	Sun May 11 13:34:29 2014 +0200
@@ -123,6 +123,12 @@
         # the middleware doesn't support len(), so content-length isn't there
         self.check_hello(out, has_length=False)
 
+    def test_absolute_path(self):
+        out, err = run_amock(
+            app=validator(hello_app),
+            data=b'GET http://127.0.0.1:8888/ HTTP/1.0\n\n')
+        self.check_hello(out, has_length=False)
+
     def test_simple_validation_error(self):
         def bad_app(environ,start_response):
             start_response("200 OK", ('Content-Type','text/plain'))
diff -r 19464d77ec2e Lib/wsgiref/simple_server.py
--- a/Lib/wsgiref/simple_server.py	Sun Dec 29 23:38:55 2013 +0000
+++ b/Lib/wsgiref/simple_server.py	Sun May 11 13:34:29 2014 +0200
@@ -82,6 +82,10 @@
         else:
             path,query = self.path,''
 
+        # bug 21472: WSGI PATH_INFO need to be relative and BaseHTTPRequestHandler
+        # doesn't guarantee it to be that way.
+        path = urllib.parse.urlparse(path).path
+
         env['PATH_INFO'] = urllib.parse.unquote_to_bytes(path).decode('iso-8859-1')
         env['QUERY_STRING'] = query