diff -r 8e7a738c3840 Lib/test/test_docxmlrpc.py
--- a/Lib/test/test_docxmlrpc.py	Sat Nov 16 10:47:17 2013 -0500
+++ b/Lib/test/test_docxmlrpc.py	Sat Nov 16 19:46:03 2013 +0200
@@ -202,10 +202,12 @@
         """ Test that annotations works as expected """
         self.client.request("GET", "/")
         response = self.client.getresponse()
+        docstring = (b'' if sys.flags.optimize >= 2 else
+                     b'<dd><tt>Use&nbsp;function&nbsp;annotations.</tt></dd>')
         self.assertIn(
             (b'<dl><dt><a name="-annotation"><strong>annotation</strong></a>'
-             b'(x: int)</dt><dd><tt>Use&nbsp;function&nbsp;annotations.</tt>'
-             b'</dd></dl>\n<dl><dt><a name="-method_annotation"><strong>'
+             b'(x: int)</dt>' + docstring + b'</dl>\n'
+             b'<dl><dt><a name="-method_annotation"><strong>'
              b'method_annotation</strong></a>(x: bytes)</dt></dl>'),
             response.read())
 
diff -r 8e7a738c3840 Lib/test/test_functools.py
--- a/Lib/test/test_functools.py	Sat Nov 16 10:47:17 2013 -0500
+++ b/Lib/test/test_functools.py	Sat Nov 16 19:46:03 2013 +0200
@@ -1124,7 +1124,8 @@
             "Simple test"
             return "Test"
         self.assertEqual(g.__name__, "g")
-        self.assertEqual(g.__doc__, "Simple test")
+        if sys.flags.optimize < 2:
+            self.assertEqual(g.__doc__, "Simple test")
 
     @unittest.skipUnless(decimal, 'requires _decimal')
     @support.cpython_only
diff -r 8e7a738c3840 Lib/test/test_inspect.py
--- a/Lib/test/test_inspect.py	Sat Nov 16 10:47:17 2013 -0500
+++ b/Lib/test/test_inspect.py	Sat Nov 16 19:46:03 2013 +0200
@@ -2525,7 +2525,8 @@
         # Just a quick sanity check on the output
         self.assertIn(module.__name__, output)
         self.assertIn(module.__file__, output)
-        self.assertIn(module.__cached__, output)
+        if not sys.flags.optimize:
+            self.assertIn(module.__cached__, output)
         self.assertEqual(err, b'')