Index: Lib/test/test_subprocess.py
===================================================================
--- Lib/test/test_subprocess.py	(revision 83977)
+++ Lib/test/test_subprocess.py	(working copy)
@@ -23,6 +23,7 @@
 if mswindows:
     SETBINARY = ('import msvcrt; msvcrt.setmode(sys.stdout.fileno(), '
                                                 'os.O_BINARY);')
+    import winreg
 else:
     SETBINARY = ''
 
@@ -1087,6 +1088,20 @@
         self.assertEqual([(256, 999), (666,), (666,)], record_calls)
 
 
+if mswindows:
+    def check_file_assoc(test):
+        ok = False
+        try:
+            key = winreg.OpenKey(winreg.HKEY_CURRENT_USER,
+                                 (r"SOFTWARE\Microsoft\Windows\CurrentVersion"
+                                  r"\Explorer\FileExts\.py\UserChoice"))
+            val = winreg.QueryValue(key, "Progid")[0]
+            if os.path.basename(val).lower() in ("python.exe", "python_d.exe"):
+                ok = True
+        finally:
+            msg = "Incompatible file association"
+            return test if ok else unittest.skip(msg)(test)
+
 @unittest.skipUnless(mswindows, "Windows-specific tests")
 class CommandsWithSpaces (BaseTestCase):
 
@@ -1111,10 +1126,12 @@
           "2 [%r, 'ab cd']" % self.fname
         )
 
+    @check_file_assoc
     def test_shell_string_with_spaces(self):
         # call() function with string argument with spaces on Windows
         self.with_spaces('"%s" "%s"' % (self.fname, "ab cd"), shell=1)
 
+    @check_file_assoc
     def test_shell_sequence_with_spaces(self):
         # call() function with sequence argument with spaces on Windows
         self.with_spaces([self.fname, "ab cd"], shell=1)