diff -r 087d601f6df0 smtplib.py
--- a/smtplib.py	Sun Feb 15 16:37:02 2009 +0100
+++ b/smtplib.py	Sun Feb 15 16:39:16 2009 +0100
@@ -295,6 +295,10 @@
         self.sock = self._get_socket(host, port, self.timeout)
         (code, msg) = self.getreply()
         if self.debuglevel > 0: print>>stderr, "connect:", msg
+        # We need to reset the attribute so that HELO/EHLO is issued for every
+        # new connection (see issue 4142)
+        self.helo_resp = None
+        self.ehlo_resp = None
         return (code, msg)
 
     def send(self, str):